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Timegated® Raman Spectroscopy for Fluorescent Materials Research

Expanding the possibilities of Raman spectroscopy in academic research

Fluorescence is one of the biggest limitations in conventional Raman spectroscopy often preventing reliable molecular analysis in biological, pharmaceutical and advanced material systems.

Timegated® Raman technology enables fast, non-destructive and label-free molecular analysis in fluorescent and optically complex materials where conventional Raman methods often fail to deliver usable spectra. By separating fast Raman signals from slower fluorescence, Timegate reveals molecular information that would otherwise remain hidden while adding the time dimension as a new layer of analytical insight.

Researchers use Timegate to explore new possibilities in materials science, photonics, semiconductors, life sciences, catalysis and pharmaceutical research.

Academic Research Challenges - Solved

Challenge

Fluorescence obscure Raman signals

Thermal interference obscure Raman signals

Weak signals in complex or novel materials

Limited ability to study dynamic processes, in e.g. operando measurements

Timegate solution

Separates Raman signals from background for fluorescent emission

Operates in high thermal emission and ambient light

Enhances signal-to-noise ratio, revealing insights from difficult samples due to ability to use 532nm excitation

Pulsed laser 150kHz enables extreme fast measurements

 

Benefits of Timegated® Raman Spectroscopy for Researchers

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Measure Challenging Samples

See the unseen - Analyze fluorescent samples and measure even in highly elevated temperatures up to 2300°C

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Novel, Higher-Quality Data

Opens access to high-resolution time-stamped Raman and fluorescence signals forming 3D data cube

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Fast and Non-Destructive Analysis

Perform in situ measurements without altering or damaging your samples.

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Expands research areas

Modular instrument structure enables wider application areas by multiple research groups

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Reference

Advancing Biomedical Research at Duquesne University

Researchers at Duquesne University are using Timegated® Raman technology to overcome fluorescence challenges and gain clearer molecular insights in complex biological samples. See how advanced spectroscopy supports faster, more reliable academic discoveries.

Real world collaborations

Bioreactor with green liquid.
Lessons from ROBA: Building Robust Algae Cultivation

The ROBA (Robust Algae Systems) project explored how to make large-scale algae cultivation more reliable and economically viable. By combining advanced monitoring technologies, modelling, and bioprocess expertise, the project addressed key challenges such as contamination control and process stability.

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Real-Time Bioprocess Monitoring with Time-Gated Raman at KTH

At KTH Royal Institute of Technology, Time-gated Raman spectroscopy enables non-destructive, real-time monitoring of key metabolites in stem cell bioproduction, improving process control and supporting the shift toward continuous, automated biomanufacturing. 

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Higher Sensitivity, Clearer Signals in Bioprocessing

A collaborative study led by Duquesne University shows how Time-Gated Raman outperforms conventional Raman by improving signal-to-noise ratio and enabling detection of key metabolites at lower concentrations—unlocking real-time process insight.

 

Test your samples with Timegated Raman!

Whether you’re working in life sciences, materials research, or fundamental chemistry, Timegate experts can help optimize your analytical strategies with fluorescence-free Raman insights.